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Keap1–Nrf2 pathway: A promising target towards lung cancer prevention and therapeutics

OBJECTIVES: Drugs for targeted therapy have become a new strategy of adjuvant therapy for treatment of lung cancer. The Keap1 (kelch-like ECH-associated protein 1)–Nrf2 (nuclear factor erythroid 2-related factor 2) pathway is recognized to be critical in regulating genes related to the cellular prot...

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Detalles Bibliográficos
Autores principales: Tong, Ying-Hui, Zhang, Bo, Fan, Yun, Lin, Neng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643752/
https://www.ncbi.nlm.nih.gov/pubmed/29063005
http://dx.doi.org/10.1016/j.cdtm.2015.09.002