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Comparative genomic analyses highlight the contribution of pseudogenized protein-coding genes to human lincRNAs

BACKGROUND: The regulatory roles of long intergenic noncoding RNAs (lincRNAs) in humans have been revealed through the use of advanced sequencing technology. Recently, three possible scenarios of lincRNA origins have been proposed: de novo origination from intergenic regions, duplication from other...

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Detalles Bibliográficos
Autores principales: Liu, Wan-Hsin, Tsai, Zing Tsung-Yeh, Tsai, Huai-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644071/
https://www.ncbi.nlm.nih.gov/pubmed/29037146
http://dx.doi.org/10.1186/s12864-017-4156-x