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Trypanosoma cruzi specific mRNA amplification by in vitro transcription improves parasite transcriptomics in host-parasite RNA mixtures

BACKGROUND: Trypanosomatids are a group of protozoan parasites that includes the etiologic agents of important human illnesses as Chagas disease, sleeping sickness and leishmaniasis. These parasites have a significant distinction from other eukaryotes concerning mRNA structure, since all mature mRNA...

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Detalles Bibliográficos
Autores principales: Kessler, Rafael Luis, Pavoni, Daniela Parada, Krieger, Marco Aurelio, Probst, Christian Macagnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644099/
https://www.ncbi.nlm.nih.gov/pubmed/29037144
http://dx.doi.org/10.1186/s12864-017-4163-y