Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer

BACKGROUND: Immunostimulatory therapies targeting immune-suppressive pathways produce durable responses in advanced solid tumors. Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting oxidoreductase that catalyzes the degradation of tryptophan to kynurenine. IDO induces immune tolerance by downregu...

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Detalles Bibliográficos
Autores principales: Carvajal-Hausdorf, Daniel E., Mani, Nikita, Velcheti, Vamsidhar, Schalper, Kurt A., Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644103/
https://www.ncbi.nlm.nih.gov/pubmed/29037255
http://dx.doi.org/10.1186/s40425-017-0285-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644103/
https://www.ncbi.nlm.nih.gov/pubmed/29037255
http://dx.doi.org/10.1186/s40425-017-0285-7

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