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LPS regulates the expression of glucocorticoid receptor α and β isoforms and induces a selective glucocorticoid resistance in vitro

BACKGROUND: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in vitro. METHODS: U-2 OS cell lines expressing GR isoforms, different cell lines (C...

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Detalles Bibliográficos
Autores principales: Molina, Maria Luisa, Guerrero, Julia, Cidlowski, John A., Gatica, Héctor, Goecke, Annelise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644185/
https://www.ncbi.nlm.nih.gov/pubmed/29075152
http://dx.doi.org/10.1186/s12950-017-0169-0