جاري التحميل…
YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer
BACKGROUND: Chemotherapy resistance remains a major challenge in cancer treatment. COX-2 (cyclooxygenase 2) is involved in drug resistance and poor prognosis of many neoplastic diseases or cancers. However, investigations identifying new modulators of COX-2 pathway and searching for new chemicals ta...
المؤلفون الرئيسيون: | , , , , , , , , , , , |
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التنسيق: | Online مقال نص |
اللغة: | English |
منشور في: |
BioMed Central
2017
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الموضوعات: | |
الوصول للمادة أونلاين: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644195/ https://www.ncbi.nlm.nih.gov/pubmed/29037225 http://dx.doi.org/10.1186/s13046-017-0612-3 |