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ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?
BACKGROUND: Programmed ribosomal frameshifting (PRF) is a gene expression mechanism which enables the translation of two N-terminally coincident, C-terminally distinct protein products from a single mRNA. Many viruses utilize PRF to control or regulate gene expression, but very few phylogenetically...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644247/ https://www.ncbi.nlm.nih.gov/pubmed/29037253 http://dx.doi.org/10.1186/s13062-017-0195-0 |