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The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke

BACKGROUND: Reactive astrogliosis is one of the significantly pathological features in ischemic stroke accompanied with changes in gene expression, morphology, and proliferation. KCa3.1 was involved in TGF-β-induced astrogliosis in vitro and also contributed to astrogliosis-mediated neuroinflammatio...

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Detalles Bibliográficos
Autores principales: Yi, Mengni, Wei, Tianjiao, Wang, Yanxia, Lu, Qin, Chen, Gaoxian, Gao, Xiaoling, Geller, Herbert M., Chen, Hongzhuan, Yu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644250/
https://www.ncbi.nlm.nih.gov/pubmed/29037241
http://dx.doi.org/10.1186/s12974-017-0973-8