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The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke
BACKGROUND: Reactive astrogliosis is one of the significantly pathological features in ischemic stroke accompanied with changes in gene expression, morphology, and proliferation. KCa3.1 was involved in TGF-β-induced astrogliosis in vitro and also contributed to astrogliosis-mediated neuroinflammatio...
Autores principales: | Yi, Mengni, Wei, Tianjiao, Wang, Yanxia, Lu, Qin, Chen, Gaoxian, Gao, Xiaoling, Geller, Herbert M., Chen, Hongzhuan, Yu, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644250/ https://www.ncbi.nlm.nih.gov/pubmed/29037241 http://dx.doi.org/10.1186/s12974-017-0973-8 |
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