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Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?
Our recent publication demonstrates that transient inhibition of Rho-associated kinase signaling within stroma, significantly decreased in vivo primary tumor growth, metastasis and improved response to standard-of-care therapy in pancreatic cancer. Automated analysis of collagen organization in pati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644476/ https://www.ncbi.nlm.nih.gov/pubmed/29057302 http://dx.doi.org/10.1080/23723556.2017.1333973 |