Aminated nanomicelles as a designer vaccine adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes

In this study, we suggest a designer vaccine adjuvant that can mimic the drainage of pathogens into lymph nodes and activate innate immune response in lymph nodes. By the amination of multivalent carboxyl groups in poly-(γ-glutamic acid) (γ-PGA) nanomicelles, the size was reduced for rapid entry int...

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Detalles Bibliográficos
Autores principales: Song, Chanyoung, Phuengkham, Hathaichanok, Kim, Sun-Young, Lee, Min Sang, Jeong, Ji Hoon, Shin, Sung Jae, Lim, Yong Taik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644533/
https://www.ncbi.nlm.nih.gov/pubmed/29066896
http://dx.doi.org/10.2147/IJN.S144623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644533/
https://www.ncbi.nlm.nih.gov/pubmed/29066896
http://dx.doi.org/10.2147/IJN.S144623

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