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Polysaccharide-based nanoparticles for co-loading mitoxantrone and verapamil to overcome multidrug resistance in breast tumor

The aim of this study was to evaluate the potential of polyelectrolyte complex nanoparticles (PENPs) based on hyaluronic acid/chitosan hydrochloride (HA/HCS) for co-loading mitoxantrone (MTO) and verapamil (VRP) to overcome multidrug resistance in breast tumors. PENPs co-loaded with MTO and VRP (MTO...

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Detalles Bibliográficos
Autores principales: Xu, Yurui, Asghar, Sajid, Gao, Shiya, Chen, Zhipeng, Huang, Lin, Yin, Lining, Ping, Qineng, Xiao, Yanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644570/
https://www.ncbi.nlm.nih.gov/pubmed/29066886
http://dx.doi.org/10.2147/IJN.S145620