Comparative Aspects of BRAF Mutations in Canine Cancers

Activating mutations of the BRAF gene lead to constitutive activation of the MAPK pathway. The characterization and discovery of BRAF mutations in a variety of human cancers has led to the development of specific inhibitors targeting the BRAF/MAPK pathway and dramatically changed clinical outcomes i...

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Detalles Bibliográficos
Autores principales: Mochizuki, Hiroyuki, Breen, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644641/
https://www.ncbi.nlm.nih.gov/pubmed/29061943
http://dx.doi.org/10.3390/vetsci2030231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644641/
https://www.ncbi.nlm.nih.gov/pubmed/29061943
http://dx.doi.org/10.3390/vetsci2030231

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