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Elucidating the molecular basis of PPCD: Effects of decreased ZEB1 expression on corneal endothelial cell function

PURPOSE: To investigate the functional role that the zinc e-box binding homeobox 1 (ZEB1) gene, which underlies the genetic basis of posterior polymorphous corneal dystrophy 3 (PPCD3), plays in corneal endothelial cell proliferation, apoptosis, migration, and barrier function. METHODS: A human corne...

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Detalles Bibliográficos
Autores principales: Zakharevich, Marina, Kattan, Jaffer M., Chen, Judy L., Lin, Benjamin R., Cervantes, Aleck E., Chung, Doug D., Frausto, Ricardo F., Aldave, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644665/
https://www.ncbi.nlm.nih.gov/pubmed/29046608