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Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoring

Circulating cell-free DNA (cfDNA) released by tumor cells, termed ctDNA, closely reflects the heterogeneity of primary cancers and their metastases. As a noninvasive, real-time monitoring biomarker, ctDNA is a promising tool for detecting driver gene mutations, assessing tumor burden and acquired re...

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Detalles Bibliográficos
Autores principales: Chang, Yi, Tolani, Bhairavi, Nie, Xiuhong, Zhi, Xiuyi, Hu, Mu, He, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644666/
https://www.ncbi.nlm.nih.gov/pubmed/29066904
http://dx.doi.org/10.2147/TCRM.S141991