Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation

Increased sleep time and intensity quantified as low-frequency brain electrical activity after sleep loss demonstrate that sleep need is homeostatically regulated, yet the underlying molecular mechanisms remain elusive. We here demonstrate that metabotropic glutamate receptors of subtype 5 (mGluR5)...

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Detalles Bibliográficos
Autores principales: Holst, Sebastian C, Sousek, Alexandra, Hefti, Katharina, Saberi-Moghadam, Sohrab, Buck, Alfred, Ametamey, Simon M, Scheidegger, Milan, Franken, Paul, Henning, Anke, Seifritz, Erich, Tafti, Mehdi, Landolt, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644949/
https://www.ncbi.nlm.nih.gov/pubmed/28980941
http://dx.doi.org/10.7554/eLife.28751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644949/
https://www.ncbi.nlm.nih.gov/pubmed/28980941
http://dx.doi.org/10.7554/eLife.28751

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