Cargando…
Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation
Increased sleep time and intensity quantified as low-frequency brain electrical activity after sleep loss demonstrate that sleep need is homeostatically regulated, yet the underlying molecular mechanisms remain elusive. We here demonstrate that metabotropic glutamate receptors of subtype 5 (mGluR5)...
Autores principales: | Holst, Sebastian C, Sousek, Alexandra, Hefti, Katharina, Saberi-Moghadam, Sohrab, Buck, Alfred, Ametamey, Simon M, Scheidegger, Milan, Franken, Paul, Henning, Anke, Seifritz, Erich, Tafti, Mehdi, Landolt, Hans-Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644949/ https://www.ncbi.nlm.nih.gov/pubmed/28980941 http://dx.doi.org/10.7554/eLife.28751 |
Ejemplares similares
-
In vitro Cortical Network Firing is Homeostatically Regulated: A Model for Sleep Regulation
por: Saberi-Moghadam, Sohrab, et al.
Publicado: (2018) -
Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
por: Wood, Christian M., et al.
Publicado: (2018) -
The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture
por: Hong, Joohyeon, et al.
Publicado: (2016) -
Homer1a and mGluR1/5 Signaling in Homeostatic Sleep Drive and Output
por: Martin, Shenée C., et al.
Publicado: (2019) -
Dynamic changes in cerebral and peripheral markers of glutamatergic signaling across the human sleep–wake cycle
por: Weigend, Susanne, et al.
Publicado: (2019)