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Loss of foxo rescues stem cell aging in Drosophila germ line

Aging stem cells lose the capacity to properly respond to injury and regenerate their residing tissues. Here, we utilized the ability of Drosophila melanogaster germline stem cells (GSCs) to survive exposure to low doses of ionizing radiation (IR) as a model of adult stem cell injury and identified...

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Detalles Bibliográficos
Autores principales: Artoni, Filippo, Kreipke, Rebecca E, Palmeira, Ondina, Dixon, Connor, Goldberg, Zachary, Ruohola-Baker, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644957/
https://www.ncbi.nlm.nih.gov/pubmed/28925355
http://dx.doi.org/10.7554/eLife.27842