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Analysis of peripheral B cells and autoantibodies against the anti-nicotinic acetylcholine receptor derived from patients with myasthenia gravis using single-cell manipulation tools

The majority of patients with myasthenia gravis (MG), an organ-specific autoimmune disease, harbor autoantibodies that attack the nicotinic acetylcholine receptor (nAChR-Abs) at the neuromuscular junction of skeletal muscles, resulting in muscle weakness. Single cell manipulation technologies couple...

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Detalles Bibliográficos
Autores principales: Makino, Tomohiro, Nakamura, Ryuichi, Terakawa, Maki, Muneoka, Satoshi, Nagahira, Kazuhiro, Nagane, Yuriko, Yamate, Jyoji, Motomura, Masakatsu, Utsugisawa, Kimiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645109/
https://www.ncbi.nlm.nih.gov/pubmed/29040265
http://dx.doi.org/10.1371/journal.pone.0185976