NMR spectra of PB2 627, the RNA-binding domain in influenza A virus RNA polymerase that contains the pathogenicity factor lysine 627, and improvement of the spectra by small osmolytes

The influenza A virus, which has an RNA genome, requires RNA-dependent RNA polymerase for transcription and replication. The polymerase is comprised of the subunits PA, PB1, and PB2. The C-terminal RNA-binding domain in PB2 contains lysine 627 (PB2 627), which is associated with pathogenicity and ho...

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Detalles Bibliográficos
Autores principales: Kato, Yusuke S., Tanokura, Masaru, Kuzuhara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645118/
https://www.ncbi.nlm.nih.gov/pubmed/29090273
http://dx.doi.org/10.1016/j.bbrep.2017.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645118/
https://www.ncbi.nlm.nih.gov/pubmed/29090273
http://dx.doi.org/10.1016/j.bbrep.2017.09.003

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