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Dexamethasone-mediated inhibition of Glioblastoma neurosphere dispersal in an ex vivo organotypic neural assay

Glioblastoma is highly aggressive. Early dispersal of the primary tumor renders localized therapy ineffective. Recurrence always occurs and leads to patient death. Prior studies have shown that dispersal of Glioblastoma can be significantly reduced by Dexamethasone (Dex), a drug currently used to co...

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Detalles Bibliográficos
Autores principales: Meleis, Ahmed M., Mahtabfar, Aria, Danish, Shabbar, Foty, Ramsey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645119/
https://www.ncbi.nlm.nih.gov/pubmed/29040322
http://dx.doi.org/10.1371/journal.pone.0186483