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Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects

The recent Zika virus (ZIKV) outbreak in the Western hemisphere is associated with severe pathology in newborns, including microcephaly and brain damage. The mechanisms underlying these outcomes are under intense investigation. Here, we show that a 2015 ZIKV isolate replicates in multiple cell types...

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Detalles Bibliográficos
Autores principales: Hanners, Natasha W., Eitson, Jennifer L., Usui, Noriyoshi, Richardson, R. Blake, Wexler, Eric M., Konopka, Genevieve, Schoggins, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645151/
https://www.ncbi.nlm.nih.gov/pubmed/27268504
http://dx.doi.org/10.1016/j.celrep.2016.05.075