Comparison of constitutive and thiabendazole-induced expression of five cytochrome P450 genes in fourth-stage larvae of Haemonchus contortus isolates with different drug susceptibility identifies one gene with high constitutive expression in a multi-resistant isolate

Benzimidazoles (BZs) remain amongst the most widely used anthelmintic drug classes against gastro-intestinal nematode infections, although their efficacy is increasingly compromised by resistance. The primary underlying mechanisms for BZ resistance are single-nucleotide polymorphisms (SNPs) in the i...

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Detalles Bibliográficos
Autores principales: Yilmaz, Esra, Ramünke, Sabrina, Demeler, Janina, Krücken, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645160/
https://www.ncbi.nlm.nih.gov/pubmed/29035734
http://dx.doi.org/10.1016/j.ijpddr.2017.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645160/
https://www.ncbi.nlm.nih.gov/pubmed/29035734
http://dx.doi.org/10.1016/j.ijpddr.2017.10.001

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