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Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani

Widespread resistance towards antimony and reports of relapses following miltefosine treatment has severely affected the management of visceral leishmaniasis (VL) in the Indian subcontinent. Paromomycin (PMM), an aminoglycoside antibiotic, has been licensed for VL treatment in India in 2007. Althoug...

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Detalles Bibliográficos
Autores principales: Verma, Aditya, Bhandari, Vasundhra, Deep, Deepak Kumar, Sundar, Shyam, Dujardin, Jean Claude, Singh, Ruchi, Salotra, Poonam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645162/
https://www.ncbi.nlm.nih.gov/pubmed/29035735
http://dx.doi.org/10.1016/j.ijpddr.2017.10.004