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Temperature and osmotic stress dependence of the thermodynamics for binding linker histone H1(0), Its carboxyl domain (H1(0)-C) or globular domain (H1(0)-G) to B-DNA

Linker histones (H1) are the basic proteins in higher eukaryotes that are responsible for the final condensation of chromatin. In contrast to the nucleosome core histone proteins, the role of H1 in compacting DNA is not clearly understood. In this study ITC was used to measure the binding constant,...

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Detalles Bibliográficos
Autores principales: Machha, V.R., Mikek, C.G., Wellman, S., Lewis, E.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645174/
https://www.ncbi.nlm.nih.gov/pubmed/29090277
http://dx.doi.org/10.1016/j.bbrep.2017.09.009