A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers

The transcription factor Runx1 is essential for definitive haematopoiesis, and the RUNX1 gene is frequently translocated or mutated in leukaemia. Runx1 is transcribed from two promoters, P1 and P2, to give rise to different protein isoforms. Although the expression of Runx1 must be tightly regulated...

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Detalles Bibliográficos
Autores principales: Marsman, Judith, Thomas, Amarni, Osato, Motomi, O’Sullivan, Justin M., Horsfield, Julia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645309/
https://www.ncbi.nlm.nih.gov/pubmed/29042628
http://dx.doi.org/10.1038/s41598-017-13748-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645309/
https://www.ncbi.nlm.nih.gov/pubmed/29042628
http://dx.doi.org/10.1038/s41598-017-13748-8

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