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A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers
The transcription factor Runx1 is essential for definitive haematopoiesis, and the RUNX1 gene is frequently translocated or mutated in leukaemia. Runx1 is transcribed from two promoters, P1 and P2, to give rise to different protein isoforms. Although the expression of Runx1 must be tightly regulated...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645309/ https://www.ncbi.nlm.nih.gov/pubmed/29042628 http://dx.doi.org/10.1038/s41598-017-13748-8 |