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IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8(+) T cells
An effective cytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy infected cells. Vigorous immune responses can lead to activation of bystander CD8(+) T cells, but the contribution from antigen-spec...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645350/ https://www.ncbi.nlm.nih.gov/pubmed/29042682 http://dx.doi.org/10.1038/s41598-017-14000-z |