Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)

After infection of the porcine dam at about 90 days of gestation, porcine reproductive and respiratory syndrome virus (PRRSV) crosses the placenta and begins to infect fetuses. Outcomes of include abortion, fetal death and respiratory disease in newborn piglets. CD163 is the receptor for the virus....

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Detalles Bibliográficos
Autores principales: Prather, Randall S., Wells, Kevin D., Whitworth, Kristin M., Kerrigan, Maureen A., Samuel, Melissa S., Mileham, Alan, Popescu, Luca N., Rowland, Raymond R. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645351/
https://www.ncbi.nlm.nih.gov/pubmed/29042674
http://dx.doi.org/10.1038/s41598-017-13794-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645351/
https://www.ncbi.nlm.nih.gov/pubmed/29042674
http://dx.doi.org/10.1038/s41598-017-13794-2

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