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Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
After infection of the porcine dam at about 90 days of gestation, porcine reproductive and respiratory syndrome virus (PRRSV) crosses the placenta and begins to infect fetuses. Outcomes of include abortion, fetal death and respiratory disease in newborn piglets. CD163 is the receptor for the virus....
Autores principales: | Prather, Randall S., Wells, Kevin D., Whitworth, Kristin M., Kerrigan, Maureen A., Samuel, Melissa S., Mileham, Alan, Popescu, Luca N., Rowland, Raymond R. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645351/ https://www.ncbi.nlm.nih.gov/pubmed/29042674 http://dx.doi.org/10.1038/s41598-017-13794-2 |
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