The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris

The protein ataxin-3 carries a polyglutamine stretch close to the C-terminus that triggers a neurodegenerative disease in humans when its length exceeds a critical threshold. A role as a transcriptional regulator but also as a ubiquitin hydrolase has been proposed for this protein. Here, we report t...

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Detalles Bibliográficos
Autores principales: Bonanomi, Marcella, Roffia, Valentina, De Palma, Antonella, Lombardi, Alessio, Aprile, Francesco Antonio, Visentin, Cristina, Tortora, Paolo, Mauri, Pierluigi, Regonesi, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645362/
https://www.ncbi.nlm.nih.gov/pubmed/29042637
http://dx.doi.org/10.1038/s41598-017-13814-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645362/
https://www.ncbi.nlm.nih.gov/pubmed/29042637
http://dx.doi.org/10.1038/s41598-017-13814-1

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