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The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis

NIPP1 is one of the major nuclear interactors of protein phosphatase PP1. The deletion of NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult tissues. Hence, we have generated an inducible NIPP1 knockout model using a tamoxifen-inducible Cre recombinase transgene...

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Detalles Bibliográficos
Autores principales: Ferreira, Mónica, Boens, Shannah, Winkler, Claudia, Szekér, Kathelijne, Verbinnen, Iris, Van Eynde, Aleyde, Fardilha, Margarida, Bollen, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645368/
https://www.ncbi.nlm.nih.gov/pubmed/29042623
http://dx.doi.org/10.1038/s41598-017-13809-y