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The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
NIPP1 is one of the major nuclear interactors of protein phosphatase PP1. The deletion of NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult tissues. Hence, we have generated an inducible NIPP1 knockout model using a tamoxifen-inducible Cre recombinase transgene...
Autores principales: | Ferreira, Mónica, Boens, Shannah, Winkler, Claudia, Szekér, Kathelijne, Verbinnen, Iris, Van Eynde, Aleyde, Fardilha, Margarida, Bollen, Mathieu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645368/ https://www.ncbi.nlm.nih.gov/pubmed/29042623 http://dx.doi.org/10.1038/s41598-017-13809-y |
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