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Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation

Cardiac hypertrophy is an adaptive response triggered by pathological stimuli. Regulation of the synthesis and the degradation of the Ca(2+) channel inositol 1,4,5-trisphosphate receptor (IP3R) affects progression to cardiac hypertrophy. Herpud1, a component of the endoplasmic reticulum-associated d...

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Detalles Bibliográficos
Autores principales: Torrealba, Natalia, Navarro-Marquez, Mario, Garrido, Valeria, Pedrozo, Zully, Romero, Diego, Eura, Yuka, Villalobos, Elisa, Roa, Juan Carlos, Chiong, Mario, Kokame, Koichi, Lavandero, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645377/
https://www.ncbi.nlm.nih.gov/pubmed/29042597
http://dx.doi.org/10.1038/s41598-017-13797-z