Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine

Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and proteins may be one important factor contributing to developmental failure in somatic cell cloned embryos. In the present study, we found microRNA-449b (miR-449b) was highly expressed in sperm. Target gene predic...

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Detalles Bibliográficos
Autores principales: Wang, Mengyun, Gao, Yang, Qu, Pengxiang, Qing, Suzhu, Qiao, Fang, Zhang, Yong, Mager, Jesse, Wang, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645405/
https://www.ncbi.nlm.nih.gov/pubmed/29042680
http://dx.doi.org/10.1038/s41598-017-13899-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645405/
https://www.ncbi.nlm.nih.gov/pubmed/29042680
http://dx.doi.org/10.1038/s41598-017-13899-8

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