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Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake

The worldwide prevalence of diabetes has risen to 8.5% among adults, which represents a staggering rise in prevalence from 4.7% in 1980. Whilst some treatments work by increasing insulin secretion, over time their effectiveness decreases. We aim to increase insulin secretion by developing strategies...

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Detalles Bibliográficos
Autores principales: Cripps, Michael J., Hanna, Katie, Lavilla, Charlie, Sayers, Sophie R., Caton, Paul W., Sims, Craig, De Girolamo, Luigi, Sale, Craig, Turner, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645413/
https://www.ncbi.nlm.nih.gov/pubmed/29042678
http://dx.doi.org/10.1038/s41598-017-13649-w