Optimization of Sample Preparation and Instrumental Parameters for the Rapid Analysis of Drugs of Abuse in Hair samples by MALDI-MS/MS Imaging

Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) has been employed to rapidly screen longitudinally sectioned drug user hair samples for cocaine and its metabolites using continuous raster imaging. Optimization of the spatial resolution and raster speed were performe...

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Detalles Bibliográficos
Autores principales: Flinders, Bryn, Beasley, Emma, Verlaan, Ricky M., Cuypers, Eva, Francese, Simona, Bassindale, Tom, Clench, Malcolm R., Heeren, Ron M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645433/
https://www.ncbi.nlm.nih.gov/pubmed/28801836
http://dx.doi.org/10.1007/s13361-017-1766-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645433/
https://www.ncbi.nlm.nih.gov/pubmed/28801836
http://dx.doi.org/10.1007/s13361-017-1766-0

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