RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a regulator of...

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Detalles Bibliográficos
Autores principales: Pujantell, Maria, Riveira-Muñoz, Eva, Badia, Roger, Castellví, Marc, Garcia-Vidal, Edurne, Sirera, Guillem, Puig, Teresa, Ramirez, Cristina, Clotet, Bonaventura, Esté, José A., Ballana, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645456/
https://www.ncbi.nlm.nih.gov/pubmed/29042669
http://dx.doi.org/10.1038/s41598-017-13580-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645456/
https://www.ncbi.nlm.nih.gov/pubmed/29042669
http://dx.doi.org/10.1038/s41598-017-13580-0

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