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Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation

Neuropeptides and their receptors play a role in physiological responses such as appetite, stress and inflammatory pain. With neuropeptides having such diverse and important physiological roles, knocking-out the genes encoding them, their receptors, parts of their regulatory sequences, or reproducin...

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Detalles Bibliográficos
Autores principales: Hay, Elizabeth A., Knowles, Christopher, Kolb, Andreas, MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645574/
https://www.ncbi.nlm.nih.gov/pubmed/28038787
http://dx.doi.org/10.1016/j.npep.2016.11.010