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LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8(+) T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection

Integrins mediate the lymphocyte migration into an infected tissue, and these cells are essential for controlling the multiplication of many intracellular parasites such as Trypanosoma cruzi, the causative agent of Chagas disease. Here, we explore LFA-1 and VLA-4 roles in the migration of specific C...

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Detalles Bibliográficos
Autores principales: Ferreira, Camila Pontes, Cariste, Leonardo Moro, Santos Virgílio, Fernando Dos, Moraschi, Barbara Ferri, Monteiro, Caroline Brandão, Vieira Machado, Alexandre M., Gazzinelli, Ricardo Tostes, Bruna-Romero, Oscar, Menin Ruiz, Pedro Luiz, Ribeiro, Daniel Araki, Lannes-Vieira, Joseli, Lopes, Marcela de Freitas, Rodrigues, Mauricio Martins, de Vasconcelos, José Ronnie Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645645/
https://www.ncbi.nlm.nih.gov/pubmed/29081775
http://dx.doi.org/10.3389/fimmu.2017.01291