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Tandem trimer pyrrole–imidazole polyamide probes targeting 18 base pairs in human telomere sequences

The binding of molecules to specific DNA sequences is important for imaging genome DNA and for studying gene expression. Increasing the number of base pairs targeted by these molecules would provide greater specificity. N-Methylpyrrole–N-methylimidazole (Py–Im) polyamides are one type of such molecu...

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Detalles Bibliográficos
Autores principales: Kawamoto, Yusuke, Sasaki, Asuka, Hashiya, Kaori, Ide, Satoru, Bando, Toshikazu, Maeshima, Kazuhiro, Sugiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645774/
https://www.ncbi.nlm.nih.gov/pubmed/29308145
http://dx.doi.org/10.1039/c4sc03755c