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Flaws in foldamers: conformational uniformity and signal decay in achiral helical peptide oligomers

Although foldamers, by definition, are extended molecular structures with a well-defined conformation, minor conformers must be populated at least to some extent in solution. We present a quantitative analysis of these minor conformers for a series of helical oligomers built from achiral but helicog...

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Detalles Bibliográficos
Autores principales: Le Bailly, Bryden A. F., Byrne, Liam, Diemer, Vincent, Foroozandeh, Mohammadali, Morris, Gareth A., Clayden, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645781/
https://www.ncbi.nlm.nih.gov/pubmed/29308146
http://dx.doi.org/10.1039/c4sc03944k