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Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation
There are five active prostanoid metabolites of arachidonic acid (AA) that have widespread and varied physiologic functions throughout the body, including regulation of gastrointestinal mucosal blood flow, renal haemodynamics and primary haemostasis. Each prostanoid has at least one distinct recepto...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645826/ https://www.ncbi.nlm.nih.gov/pubmed/29067176 http://dx.doi.org/10.1002/vms3.13 |