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Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation

There are five active prostanoid metabolites of arachidonic acid (AA) that have widespread and varied physiologic functions throughout the body, including regulation of gastrointestinal mucosal blood flow, renal haemodynamics and primary haemostasis. Each prostanoid has at least one distinct recepto...

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Detalles Bibliográficos
Autores principales: Kirkby Shaw, Kristin, Rausch‐Derra, Lesley C., Rhodes, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645826/
https://www.ncbi.nlm.nih.gov/pubmed/29067176
http://dx.doi.org/10.1002/vms3.13

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