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Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma

Spontaneous canine malignant melanoma provides an excellent pre‐clinical model to study DNA vaccines for melanoma immunotherapy. A USDA‐approved xenogeneic human tyrosinase (huTYR) plasmid DNA vaccine delivered intramuscularly induces detectable immune responses and has clinical activity in some dog...

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Detalles Bibliográficos
Autores principales: Zuleger, Cindy L., Kang, Chulhi, Ranheim, Erik A., Kurzman, Ilene D., Macklin, Michael D., Newton, Michael A., Wolchok, Jedd D., Vail, David M., Eriksson, Elof, Albertini, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645840/
https://www.ncbi.nlm.nih.gov/pubmed/29067210
http://dx.doi.org/10.1002/vms3.65