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Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer
BACKGROUND: The conversion from estrogen-dependent to estrogen-independent state of ER+ breast cancer cells is the key step to promote resistance to endocrine therapies. Although the crucial role of MAPK/ERK signaling pathway in estrogen-independent breast cancer cell growth is well established, the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645922/ https://www.ncbi.nlm.nih.gov/pubmed/29041978 http://dx.doi.org/10.1186/s12943-017-0727-3 |