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Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer

BACKGROUND: The conversion from estrogen-dependent to estrogen-independent state of ER+ breast cancer cells is the key step to promote resistance to endocrine therapies. Although the crucial role of MAPK/ERK signaling pathway in estrogen-independent breast cancer cell growth is well established, the...

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Detalles Bibliográficos
Autores principales: Peng, Wan-xin, Huang, Jian-guo, Yang, Liu, Gong, Ai-hua, Mo, Yin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645922/
https://www.ncbi.nlm.nih.gov/pubmed/29041978
http://dx.doi.org/10.1186/s12943-017-0727-3