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Shift in the function of netrin-1 from axon outgrowth to axon branching in developing cerebral cortical neurons

BACKGROUND: Netrin-1, a multifunctional axon guidance cue, elicits axon outgrowth via one of its receptors deleted in colorectal cancer (DCC) in several types of neurons, including cerebral cortical neurons of embryonic mice. However, we and others have observed de novo formation of axon branches wi...

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Detalles Bibliográficos
Autores principales: Matsumoto, Hideko, Nagashima, Masabumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645936/
https://www.ncbi.nlm.nih.gov/pubmed/29041904
http://dx.doi.org/10.1186/s12868-017-0392-x