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Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis

BACKGROUND: Mildly elevated lactate levels (i.e., 1–2 mmol/L) are increasingly recognized as a prognostic finding in critically ill patients. One of several possible underlying mechanisms, microcirculatory dysfunction, can be assessed at the bedside using sublingual direct in vivo microscopy. We aim...

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Detalles Bibliográficos
Autores principales: Vellinga, Namkje A. R., Boerma, E. Christiaan, Koopmans, Matty, Donati, Abele, Dubin, Arnaldo, Shapiro, Nathan I., Pearse, Rupert M., van der Voort, Peter H. J., Dondorp, Arjen M., Bafi, Tony, Fries, Michael, Akarsu-Ayazoglu, Tulin, Pranskunas, Andrius, Hollenberg, Steven, Balestra, Gianmarco, van Iterson, Mat, Sadaka, Farid, Minto, Gary, Aypar, Ulku, Hurtado, F. Javier, Martinelli, Giampaolo, Payen, Didier, van Haren, Frank, Holley, Anthony, Gomez, Hernando, Mehta, Ravindra L., Rodriguez, Alejandro H., Ruiz, Carolina, Canales, Héctor S., Duranteau, Jacques, Spronk, Peter E., Jhanji, Shaman, Hubble, Sheena, Chierego, Marialuisa, Jung, Christian, Martin, Daniel, Sorbara, Carlo, Bakker, Jan, Ince, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646128/
https://www.ncbi.nlm.nih.gov/pubmed/29047411
http://dx.doi.org/10.1186/s13054-017-1842-7