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T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

BACKGROUND: Processes and mechanisms responsible for systemic immune suppression in early-stage cervical cancer remain substantially underinvestigated. In this work, we focused on studying the frequencies of circulating regulatory T (CD4 and CD8 Tregs) and NK (NKregs) cells in parallel with assessme...

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Detalles Bibliográficos
Autores principales: Kurmyshkina, Olga V., Kovchur, Pavel I., Schegoleva, Ludmila V., Volkova, Tatyana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646147/
https://www.ncbi.nlm.nih.gov/pubmed/29075318
http://dx.doi.org/10.1186/s13027-017-0166-1