Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure

BACKGROUND: Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference popul...

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Detalles Bibliográficos
Autores principales: Kabisch, Maria, Hamann, Ute, Lorenzo Bermejo, Justo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646149/
https://www.ncbi.nlm.nih.gov/pubmed/29041903
http://dx.doi.org/10.1186/s12864-017-4208-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646149/
https://www.ncbi.nlm.nih.gov/pubmed/29041903
http://dx.doi.org/10.1186/s12864-017-4208-2

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